Endocrine Abstracts

Hirsutism, development of terminal body hair in women in unexpected areas, may result from different etiologies; 4.3% being nonclassical congenital adrenal hyperplasia (NCCAH) and acromegaly being one of the rarests. We here present a severe hirsutism case with acromegaly and NCCAH.Case: A 30-year-old woman with headache and visual field abnormalities was consultated by our clinic about her cranial imaging revealing a macroadenoma in pituitary localizati...

Anaemia prevalence is reported between 5 and 31.8% in patients with PHPT. Anaemia in PHPT shows correlations with serum calcium, PTH, alkaline phosphatase levels, severity of the bone disease and PHPT duration. In this study we compared pre-operative and post-operative haemogram parameters of patients with PHPT who received a parathyroidectomy at our department. We determined the prevelance of pre-operative anaemia, thrombocytopenia, neutropenia and observed if any of this par...

Introduction: Neutrophil/lymphocyte ratio (NLR) is an indicative of the acute phase response. It is a significant indicator of the systemic inflammation, and considered as a poor prognosis indicator in various disease. We aimed to evaluate NLR and its determinants in acromegaly patients.Patients and methods: A retrospective chart review of 40 patients with acromegaly and 45 age and sex matched healthy individuals was performed. Patients with active infec...

Idiopathic hypoparathyroidism (IHP) is an uncommon disease in which soft tissue calcifications may be seen. We report a case with IHP with asymptomatic hypocalcemia and features of ankylosing spondylitis (AS).Case: A 58-year-old male patient was referred to our department due to incidentally discovered hypocalcemia when admitted with blurred speech, gait and posture abnormalities. He had had a generalized convulsion 19 years ago. On physical examination,...

Introduction: Vitamin D deficiency may be an important predisposing factor for infections as well as autoimmune diseases in old individuals. Neutrophil/lymphocyte ratio (NLR), is a meaningful indicator of inflammation throughout the body. In this study we aimed to show, whether or not a relationship exists between vitamin D levels and NLR in patients older than 65 years.Materials and method: Data of 82 patients over 65 years of age was retrospectively ex...

Introduction: Diabetes is characterized by an increase in abdominal fat. This results in a decrease in lean body mass and increase in insulin resistance. In this study, we aimed to evaluate the possible relationship between body composition and insulin regimen modality in type 1 diabetic patients.Materials and methods: Ninety-two type 1 diabetic patient followed in our institution were included in the study. Patients were classified into two groups accor...

Introduction: Acromegaly is a rare disease characterized by GH and IGF1 hypersecretion and increased cardiovascular mortality. Ultrasonographic measurement of carotid intima media thickness (CIMT) gives substantial information about early atherosclerosis. We aimed to evaluate CIMT and its determinants in a group of acromegaly patient.Patients and methods: Forty-four acromegaly patient and 43 age, sex and body mass index (BMI) matched healthy controls wer...

Background: Primary empty sella is an anatomical term defining the herniation of subarachnoid space within the sella turcica without an underlying factor such as pituitary tumor, surgery, irradiation or trauma.Patients and methods: We retrospectively evaluated clinical, hormonal and radiological data of the patients with primary empty sella syndrome followed in our institution between 2001 and 2012.Results: Ninety-four patients (80...

Introduction: The growth promoting effects of GH and IGF1 has lead to increasing number of cancer surveillence studies in acromegaly so far. We herein aimed to present the prevalance of cancer in acromegaly patients followed in our institution.Patients and design: We retrospectively analyzed medical records of 151 patients with acromegaly (83 females) followed in our department from 2001 to 2012.Results: Overall, cancer was detecte...

TSH supression therapy with thyroid hormone is a mainstay of thyroid cancer treatment. Effectiveness of thyroid hormone therapy may be disrupted by nonadherence of the patient, interfering drugs, foods and intestinal disorders. We here present a case of papillary thyroid cancer with unsuccessful supression therapy.Case: A 38 year old woman, underwent total thyroidectomy for euthyroid multinodular goitre, with a pathological diagnosis of papillary thyroid...